Pure Encapsulations DIM & Detox is a vegan formula that supports natural liver detoxification and healthy cell growth. Made from broccoli concentrate to promote phase 2 detoxification pathways and healthy cell metabolism and other naturally-sourced ingredients, DIM Detox is pure, potent and bioavailable. Free from allergens, pesticides, unnecessary fillers and binders and allergens, Pure Encapsulations is committed to quality control and ensures every supplements is made in a facility following cGMP guidelines and is FDA-inspected. [VCAP]
Each capsule contains:
BioResponse DIM (complex of starch, 3,3-diindolylmethane, vitamin E (tocophersolan), phosphatidylcholine, silica) (providing DIM (3,3-diindolylmethane) 12.5 mg) 50mg
Calcium-D-glucarate 50mg
Broccoli (Brassica oleracea var. italica) Sprout Extract (20:1, 1000 mg dried equivalent; standardized to contain 200 mcg sulforaphane) 50mg
HMRlignan 7-Hydroxymatairesinol Potassium Acetate 5mg
DL-Alpha-Lipoic Acid 100mg
N-Acetyl-L-Cysteine 100mg
Milk Thistle (Silybum marianum extract (seed) (standardized to contain 80% silymarin) 75mg
L-Methionine 100mg
Glycine 50mg
Taurine 50mg
Non-Medicinal Ingredients:
Hydroxypropyl Methylcellulose, Hypoallergenic Plant Cellulose, Ascorbyl Palmitate, Purified Water
Important Information:
Do not use this product if you are pregnant, breastfeeding or taking antibiotics or nitroglycerin. Consult a healthcare practitioner prior to use if you have diabetes, kidney stones, liver disorder, symptoms of low estrogen, are taking contraceptives, hormone replacement therapy, any medication or natural health products or are attempting to conceive. Stop use and consult a healthcare practitioner if symptoms persist or worsen, if you develop liver-related symptoms, symptoms of low estrogen, or if you experience sweating, paleness, chill, headache, dizziness or confusion. Stop use if allergy occurs. Ensure to drink enough fluid before, during, and after exercise. Keep out of the reach of children.
Dosage
Adults: Take 2 capsules daily with meals, or as directed by a healthcare practitioner.
Quality Vitamins Trusted by Healthcare Professionals
Pure Encapsulations offers hypoallergenic natural health supplements that undergo third-party testing for purity and potency. Pure Encapsulations is a leading brand among healthcare practitioners and is free from gluten, GMO, fillers and preservatives. Top-selling vitamins and minerals include; Magnesium Glycinate and B-Complex Plus. With Pure Encapsulations you have quality assurance.
DIM
What Is DIM?
Diindolylmethane (DIM) is a natural condensation product of indole-3-carbinol (I3C), which is found in cruciferous (Brassica family) vegetables such as cauliflower, cabbage, cress, bok choy, broccoli,
kale, and similar green leaf vegetables.
Part of this effect is likely due to DIM's role in
estrogen
metabolism balance in the body (see below).There is also preliminary research implicating DIM as an immunomodulating supplement against auto-immune disease, although further research is required.
DIM And I3C
DIM is a natural diindole condensation product of I3C created during digestion in the presence of sufficient stomach acid. This chemical is more shelf-stable and more easily absorbed in the digestive tract than I3C. Recent research has implied that benefits previously attributed to I3C may actually be the result of DIM created through conversion in the digestive tract. Further research is required to confirm these results before attributing all of the beneficial effects of I3C to DIM.
DIM And Estrogen Balance
Both males and females produce estrogen naturally in their bodies, although women produce significantly higher levels. This endogenous estrogen can either be metabolized to 16alpha-hydroxyestrone (16OHE1) or 2-hydroxyestrone (2OHE1). Research suggests that DIM preferentially promotes the metabolism of estrogen to the less harmful, and less active 2-hydroxyestrone form.
DIM & Male Hormones
It has also been found to reduce PSA expression, and act as a strong competitive inhibitor of dihydrotestosterone (DHT), a hormone responsible for many male-associated problems. DIM is likely the first example of a pure androgen receptor blocker extracted from plants.
DIM And Age-Related Muscle Loss In Men
As men age, they naturally produce lowered levels of
testosterone
and over time estrogen can be found in higher concentrations in their tissues, resulting in a loss of muscle mass. Testosterone is one of the hormones responsible for anabolic muscle growth in the body. There is a natural balance of the conversion of testosterone to estrogen in the body. As noted above, DIM has been shown to regulate the metabolism of estrogen in the body to be less active. This helps to shift the hormonal balance more favourably in men entering andropause ("male
menopause
").
How Can I Take DIM?
DIM can be absorbed directly from eating cruciferous vegetables from the Brassica family, such as cauliflower, cabbage, cress, bok choy, broccoli, kale, and similar green leaf vegetables. It is important that if cooking these vegetables, not to boil them, as it will significantly reduce their beneficial content.
In order to get higher doses, DIM can be supplemented using capsules or combination formulas. When supplementing DIM, it is generally taken at between 100 and 200 mg per day. A dose of 200 mg was found by a preliminary safety study to be the highest dose that did not produce negative side effects in the research group.
Important Information
DIM is considered safe in both food/diet amounts and therapeutic dosages. Excess supplementation may result in skin rashes, increased liver
enzymes, as well as nausea and vomiting. Overuse and/or preventative use of DIM is further ill advised because of its hormone altering effects in normal individuals that can result in systemic hormone dysregulation. For this reason, do not use as a supplement while pregnant or breastfeeding.
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Product Details
DIM
What Is DIM?
Diindolylmethane (DIM) is a natural condensation product of indole-3-carbinol (I3C), which is found in cruciferous (Brassica family) vegetables such as cauliflower, cabbage, cress, bok choy, broccoli,
kale, and similar green leaf vegetables.
Part of this effect is likely due to DIM's role in
estrogen
metabolism balance in the body (see below).There is also preliminary research implicating DIM as an immunomodulating supplement against auto-immune disease, although further research is required.
DIM And I3C
DIM is a natural diindole condensation product of I3C created during digestion in the presence of sufficient stomach acid. This chemical is more shelf-stable and more easily absorbed in the digestive tract than I3C. Recent research has implied that benefits previously attributed to I3C may actually be the result of DIM created through conversion in the digestive tract. Further research is required to confirm these results before attributing all of the beneficial effects of I3C to DIM.
DIM And Estrogen Balance
Both males and females produce estrogen naturally in their bodies, although women produce significantly higher levels. This endogenous estrogen can either be metabolized to 16alpha-hydroxyestrone (16OHE1) or 2-hydroxyestrone (2OHE1). Research suggests that DIM preferentially promotes the metabolism of estrogen to the less harmful, and less active 2-hydroxyestrone form.
DIM & Male Hormones
It has also been found to reduce PSA expression, and act as a strong competitive inhibitor of dihydrotestosterone (DHT), a hormone responsible for many male-associated problems. DIM is likely the first example of a pure androgen receptor blocker extracted from plants.
DIM And Age-Related Muscle Loss In Men
As men age, they naturally produce lowered levels of
testosterone
and over time estrogen can be found in higher concentrations in their tissues, resulting in a loss of muscle mass. Testosterone is one of the hormones responsible for anabolic muscle growth in the body. There is a natural balance of the conversion of testosterone to estrogen in the body. As noted above, DIM has been shown to regulate the metabolism of estrogen in the body to be less active. This helps to shift the hormonal balance more favourably in men entering andropause ("male
menopause
").
How Can I Take DIM?
DIM can be absorbed directly from eating cruciferous vegetables from the Brassica family, such as cauliflower, cabbage, cress, bok choy, broccoli, kale, and similar green leaf vegetables. It is important that if cooking these vegetables, not to boil them, as it will significantly reduce their beneficial content.
In order to get higher doses, DIM can be supplemented using capsules or combination formulas. When supplementing DIM, it is generally taken at between 100 and 200 mg per day. A dose of 200 mg was found by a preliminary safety study to be the highest dose that did not produce negative side effects in the research group.
Important Information
DIM is considered safe in both food/diet amounts and therapeutic dosages. Excess supplementation may result in skin rashes, increased liver
enzymes, as well as nausea and vomiting. Overuse and/or preventative use of DIM is further ill advised because of its hormone altering effects in normal individuals that can result in systemic hormone dysregulation. For this reason, do not use as a supplement while pregnant or breastfeeding.
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